Appendix 1
The Chronological Development of The Unborn Child

 

Fourth Week

 

Timing

Source

The eyes begin to develop.
Early in the 4th week Larsen, p 252
The development of the eye is first evident. Beginning of the 4th week after fertilization Moore, p 492

The facial primordia begin to appear.

Early in 4th week after fertilization Moore, p 236
The cardiovascular system has formed.
4th week after fertilization. Williams,
p 161
The esophagus is developing. 4th week of development Sadler, p 274
The gallbladder is developing. 4th week of development Sadler, p 274.
The heart begins to pump. 4th week of development Sadler, p 77
The liver is developing. 4th week of development Sadler, p 274
The liver bud sprouts. 4th week Larsen, p 157
The lung bud develops. 4th week of fertilization Moore, p 262
Heart activity can be measured with transvaginal ultrasonic scanning. 4th week of fertilization Williams, p 1027
The pancreas is developing. 4th week of development

Sadler, p 274

 

The pharynx is developing. 4th week Sadler, p 274
The stomach appears. 4th week of development Sadler, p 276
The trachea is developing. During the 4th week Sadler, p 274
The thyroid gland primordium first appears. Late in 4th week of development Larsen, p249
The anlage (i.e. the earliest discernible indication) of the central nervous system is present. End of 4th week of development Larsen, p 52
Limb buds become visible. End of 4th week of development Sadler, 7th edition, p 154
Nasal placodes - the primordia of the nose and the nasal cavities - have developed. End of 4th week after fertilization Moore, p239
The beginnings of many of the organ systems, including the cardiovascular system, are established. End of 4th week after fertilization Moore, p 91
The development of the tongue begins. Late in 4th week of development Larsen, p 247
The first sign of the tongue's development appears, the median tongue bud. End of 4th week after fertilization Moore, p 233
The lung bud appears. Approximately 4th week of development Sadler, p 260
The tongue appears. Approximately 4th week Sadler, p 362
Facial development mostly occurs. 4th -8th weeks after fertilization Moore, p 236
Tooth buds form from dental lamina. 4th - 8th weeks of development Larsen, p 304
The first sign of the developing internal ear occurs. Approximately day 22 Sadler, p 382
The developing eye appears. Day 22 Sadler, p 394
The heart begins to pump. Day 22 after fertilization Larsen, p xi
The heart begins to beat. Day 22 after fertilization Moore, p 5; Larsen, p 104
The heart begins to beat. Day 22 after fertilization England, p 104
The lung bud is present. Day 22 Sadler, p 210
The lung bud appears. Days 22-24 Larsen, p 82.
The primorida of the ears are present. Day 23 after fertilization Moorek p 5
The primordia of the eyes are present. Day 23 after fertilization Moore, p. 5
The heart starts to beat. Day 24 after fertilization Rugh, p 17
Blood begins to circulate throughout the embryo. Day 24 Larsen, p 104
Upper limb buds appear. Day 24 of development Larsen, p 209
Otic placodes appear. Days 24-25 Sadler, p 110
The liver bud is present. Approximately day 25 Sadler, p 281
The stomach is developing. Approximately day 25 Sadler, p 281
Upper limb buds appear. Day 26 after fertilization Larsen, p xi
The forebrain is developing. Day 26 after fertilization Moore, p 95
The otic pit, a sign of the first development of the internal ear, is present. Day 26 after fertilization Moore, p 95
Upper limb buds are present. Day 26 after fertilization Moore, p 5
The dorsal pancreatic bud begins to grow. Day 26 Larsen, p 158
Arm buds are present. Day 26+/-1 of development Williams, p 153
Upper limb buds appear. Days 26-27 of development Sadler, p 110
The lung bud branches into left and right bronchial buds. Days 26-28 Larsen, p 82
Lung buds may be seen. Day 27 after conception Rugh, p 43
The gallbladder appears. Days 27-30 after conception Rugh, p 42
Liver cells can be recognized as the liver. Days 27-30 after conception Rugh, p 42
The embryo grows in length from 5 millimeters to approximately 16 to 17 millimeters. Day 27 to day 37 of development Sadler, p 220
The ear placode is present. Day 28 after fertilization Sadler, front pages
The lens placode is present. Day 28 Sadler, p 90
The lens placode (the primordium of the lens) is present. Day 28 after fertilization Moore, p 92
The eye anlage is present. Day 28 after fertilization Sadler, front pages
Upper limb buds are present. Day 28 after fertilization Moore, p 92
Arm buds are present. day 28 after fertilization Sadler, front pages
The separation of the heart into a primordial artrium and ventricle can be seen. Day 28 after fertilization Moore, p 95
Lower limb buds appear. Day 28 of development Larsen, p 209
The mouth opens for the first time. Day 28 after conception Rugh, p 42
Building blocks are present for 40 pairs of muscles, which are located from the base of the skull to the bottom of the spinal column. Day 28 after conception Rugh, p 35
The spleen appears. Day 28 after fertiliztaion Larsen, p xi
The spinal cord is developing. About day 28 after fertilization Moore, p 97
The stomach is forming. About day 28 after fertilization Moore, p 97
Leg buds are present. Day 28+/-1 after fertilization Williams, p 153
Lower limb buds appear. Days 28-30 after fertilization Moore, p 91
Hindlimb buds appear. Days 28-30 of development Sadler, p 110


 


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